Research Articles

Scientific insights and research findings on peptide applications in laboratory studies.

February 2026

Triple-Receptor Agonism in Metabolic Research

Research Focus: GLP-3 RT

Exploring the synergistic effects of simultaneous GLP-1, GIP, and glucagon receptor activation in laboratory metabolic studies.

Key Findings:

▸Superior weight reduction compared to single-receptor approaches in preclinical models
▸Enhanced glucose homeostasis through multi-pathway activation
▸Dose-dependent metabolic improvements across multiple markers
▸Potential applications in obesity and diabetes research

References:

Jastreboff, A. M., et al. (2023). "Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial." New England Journal of Medicine, 389(6), 514-526.

Rosenstock, J., et al. (2023). "Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial." The Lancet, 402(10401), 529-544.

Sanyal, A. J., et al. (2024). "Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 24 trial." Nature Medicine, 30(6), 1639-1647.

Abouelmagd, A. A., et al. (2025). "Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: a systematic review and meta-analysis of randomized controlled trials." Baylor University Medical Center Proceedings, 38(1), 1-10.

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January 2026

Copper Peptides in Regenerative Research

Research Focus: GHK-Cu

Comprehensive review of GHK-Cu's mechanisms in tissue repair, collagen synthesis, and cellular regeneration processes.

Key Findings:

▸Modulation of 4,000+ genes with focus on DNA repair pathways
▸25.4-fold increase in collagen IV synthesis when combined with hyaluronic acid
▸Demonstrated wound healing acceleration in diabetic models
▸Anti-inflammatory effects comparable to corticosteroids in research settings

References:

Pickart, L., et al. (2012). "GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration." BioMed Research International, 2012, Article ID 648108.

Pickart, L., & Margolina, A. (2018). "Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data." International Journal of Molecular Sciences, 19(7), 1987.

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December 2025

Neuroprotective Peptides in Cognitive Research

Research Focus: Semax

Investigation of BDNF-enhancing peptides and their applications in neurological research and cognitive function studies.

Key Findings:

▸Increased BDNF and NGF production supporting neuronal growth
▸Neuroprotective effects against oxidative stress and beta-amyloid accumulation
▸Improved cognitive markers in attention and memory research
▸Potential applications in stroke recovery and neurodegenerative research

References:

Koroleva, S. V., & Myasoedov, N. F. (2018). "Semax as a Universal Drug for Therapy and Research." Biology Bulletin, 45(6), 589-600.

Filippenkov, I. B., et al. (2020). "Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischemia-Reperfusion in Rats." Genes, 11(6), 681.

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Research Use Only: All articles reference laboratory research and preclinical studies. Products are not intended for human consumption or therapeutic use.